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✔️ 標題 : Children of the Hunt
✔️ 片長 :92 Minutes
✔️ 类型: 科幻, 动作, 冒险
✔️ 語言 :粵語 (中文字幕)
✔️ 視頻解析度: 720p-1080p HD
✔️ 視頻格式 : mp4
✔️ 上映日期: 2009-01-01
✔️ 演員 :David Stevens, Paul Shaw, Darren Dalton, Crystal Largen, Alexander Isaiah Thomas, Jacques Shy, Larry Parks / 更多...
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Synopsis :
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Claudin5Binders Enhance Permeation of Solutes across the ~ HT1080 cells stably expressing human CLDN1 CLDN2 CLDN3 CLDN4 CLDN5 CLDN6 or CLDN7 were developed as described previously Hashimoto et al 2016 P3U1 mouse myeloma cells MDCKII cells PhoenixA packaging cells and Caco2 and T84 human intestinal cells were purchased from American Type Culture Collection Manassas VA
Engineered membrane protein antigens successfully induce ~ Epitope mapping of antiCLDN5 ECR mAbs Binding reactivity of antiCLDN5 ECR mAbs against HT1080 cells expressing humanmouse CLDN5 chimera mutants was examined a Schematic illustration of the humanmouse CLDN5 mutants Single amino acid substitution D68E T75A and S151T was applied to human CLDN5
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Safety evaluation of a human chimeric monoclonal antibody ~ Claudin2 CLDN2 a poreforming tight junction protein with a tetratransmembrane domain is involved in carcinogenesis and the metastasis of some cancers Although CLDN2 is highly expressed in the tight junctions of the liver and kidney whether CLDN2 is a safe target for cancer therapy remains unknown
CLDN4 Cancer Genetics Web ~ All experiments were performed in the human SW480 SW620 HCT116 CaCo2 and HT29 colon cancer and the isogenic SkMel5 and SkMel5 Cldn3YFP melanoma cell lines Claudin expression analysis was done at protein and mRNA level which was confirmed by immunohistochemistry The CPE induced cytotoxicity was analyzed by the MTT cytotoxicity assay
Efficacy and safety evaluation of claudin‐4‐targeted ~ However CLDN‐4 is also expressed in normal tissues including the liver pancreas kidney and small intestine Whether CLDN‐4 is an effective and safe target for cancer therapy has been unclear owing to the lack of a binder with both CLDN‐4 specificity and cross‐reactivity to human and murine cells
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